Lab News
Dr. Ana I. Benítez-Mateos joined the lab as SNSF Ambizione Group Leader.
Welcome to Ana and Sofia!
[JACS] α-Synuclein Aggregation Is Triggered by Oligomeric Amyloid-β 42 via Heterogeneous Primary Nucleation
Congratulations to Devkee Vadukul and the entire group of Francesco Aprile (Imperial College, UK)!
[Nature Chemistry] The interface of condensates of the hnRNPA1 low-complexity domain promotes formation of amyloid fibrils
Congratulations to Miriam and the entire team!
[Analytical Chemistry] Multiparametric Orthogonal Characterization of Extracellular Vesicles by Liquid Chromatography Combined with In-Line Light Scattering and Fluorescence Detection
Congratulations to Karl and Marcell for the publication!
[Journal of Pharmaceutical Sciences] Comparison of the Protective Effect of Polysorbates, Poloxamer and Brij on Antibody Stability Against Different Interfaces
Congratulations to Dominik for the publication!
[Advanced Healthcare Materials] High-Yield Production of Extracellular Vesicle Subpopulations with Constant Quality Using Batch-Refeed Cultures
Congratulations to Carolina! In this paper (https://doi.org/10.1002/adhm.202202232) perfusion cultures are simulated with batch-refeed systems and their productivity is compared with that achieved using batch cultures. It is shown that a shift from batch to batch-refeed system can increase the space-time yields of a target EV subpopulation.
[Journal of Pharmaceutical Sciences] Surface-Induced Protein Aggregation and Particle Formation in Biologics: Current Understanding of Mechanisms, Detection and Mitigation Strategies
Congratulations to Marie Kopp, Fulvio Grigolato and Dominik Zürcher for the pulication of their review!